Saturday 29 September 2012


Clinical Research Approved Effects Of Terminalia Arjuna

Ancient medical scientists have mentioned the properties of arjuna herb. Indian medical knowledge known as Ayurveda goes back millennia. The Vedas and Puranas refer various materials of medical importance including herbs, plants and trees. Modern research has discovered that arjuna has antioxidant properties and may be clinically helpful in cardiovascular health.
Substances found in arjuna herb
Triterpene glycosides, arjunetin, arjunetoside, arjunaphthanoloside, together with oleanolic and arjunic acids, terminic acid, a cardenolide, and strong antioxidants (flavones, tannins, oligomeric proanthocyanidins), have been isolated from the root bark of terminalia arjuna.

Terminalia Arjuna & Our Blood Pressure:

Drug dosage dependent reduction in blood pressure and heart rate is noticed. Intravenous injection of 70% alcoholic extract of T. arjuna caused dose dependent hypotension in anaesthetized dogs. Hypotension was supposed to be due to peripheral mechanisms. Symptomatic complaints of essential hypertension viz. giddiness, insomnia, lassitude, occipital headache and poor concentration ability were relieved by arjuna. Coagulation, bleeding and prothrombin time can be reduced by oral administration of an aqueous suspension of the bark powder.

Terminalia Arjuna Protecting Our Heart:

T. arjuna has preventive and protective role in cardiovascular disorders.

Terminalia Arjuna Effects On Blood Lipids & Cholesterol:

Hypolipidemic effects i.e. normalizing the increased lipids in blood is exerted by this medicinal herb. Increased triglycerides and cholesterol levels are normalized. It enhances the turnover cycle of LDL-cholesterol in Liver - by enhancing the synthesis of Apo-B or LDL apoprotein and by inhibiting the oxidation of LDL. Lowering of Beta-Lipoproteins-lipids and increase in HDL component of lipid profile results from suppression of cholesterol biosynthesis in Liver.

Terminalia Arjuna & Ischemic Heart Diseases Like Angina & Myocardial Infarction:

Its bark is anti-ischemic, cardiac protective and cardio-tonic. Efficacy of T. arjuna is established by a double blind, placebo controlled study in Chronic Stable Angina. Its bark extract in the dosage of 500 mg four times a day caused improvement in clinical and treadmill exercise parameters as compared to placebo. The benefits were found to be comparable with Isosorbide mononitrate (40 mg per day) and with good tolerance.  Digitalis or nitroglycerine  only strengthen and restores heart beat with no nutritive effect on the heart muscle itself.
T. arjuna protects the heart of rabbit against ischemic reperfusion injury. The role of anti-oxidant enzymes and heart shock proteins were explored. It prevents the oxidative stress, myocardial injury and hemodynamic effects induced by ischemic reperfusion injury. This study provides the scientific basis for its preventive role for IHD or ischemic heart disease.
In another study, arjuna was found to augment endogenous antioxidant compounds of rat heart and to prevent the myocardium from isoproterenol induced myocardial ischemic reperfusion injury.
Yet another napthanol glycoside from T. arjuna demonstrated antioxidant and nitric oxide inhibiting activities. Arjungenin was found to be the most active as direct free radical scavenger and inhibitor for the hypochlorous acid production. Its glycoside arjunetin was also 50% active. These again prove its cardioprotective role.
Thus it has proven prostaglandin enhancing and coronary risk modulating property. More than 6 million people are suffering from Angina in US. In the long term arjuna was found to be greatly effective without the nasty side effects and without loss of efficacy.

Terminalia Arjuna & Coenzyme Q10:

This Coenzyme Q10 is being prescribed to cardiac patients for preventing heart attacks. Its protective cardiovascular effect was due to its combined effects like hypolipidemic effect, drug dosage dependent reduction in heart rate and blood pressure.

Terminalia Arjuna As Antioxidant:

The bark powder of terminalia arjuna showed antioxidant action comparable with Vit. E. The extra benefit was the hypocholesterolemic effect.

Terminalia Arjuna & Congestive Cardiac Failure:

CCF also positively responded to this medicinal herb.

Terminalia Arjuna With Anti-Mutagenic Potential:

In the J Environ Pathol Toxicol Oncol 2001;20:9-14 documents a study that indicates its anti-mutagenic or anti-cancer potential and advised to explore it further. Arjuna has compounds that protect against DNA damage from toxins. A substance in Arjuna, causrinin, inhibits breast cancer cell growth. Casuarinin from the Bark of T. arjuna Induces Apoptosis and Cell Cycle Arrest in Human Breast Adenocarcinoma MCF-7 Cells.
Tannins and triterpenes (The Phenolic fractions) in T. arjuna have been found to show antigenotoxic or antimutagenic effects.

Terminalia Arjuna Reversing The Damage By Chronic Smoking:

Smoking causes endothelial dysfunction, an early event of Atherosclerosis. It is mediated through mainly oxidative stress process. Two weeks of therapy with this medicinal herb leads to reversal of impaired function in endothelium of smokers.


  1. Hypertension & Tachycardia where heart beat is increased. Use it as adjuvant or alternative medicine in consultation with qualified herbalist.
  2. For increased level of cholesterol in blood - Hypercholesterolemia.
  3. As a cardiac protective and supportive herbal supplement.

1 comment:

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